Goal of treatment for Diabetes

The main goal of treating diabetes is to lower blood sugar to a normal level. Lowering and controlling blood sugar may help prevent or delay complications of diabetes such as heart disease, kidney disease, blindness and amputation.
High blood sugar can be lowered by diet and exercise and by certain medicines.

Treatment of Type 2 Diabetes with Sitagliptin (Januvia)
Type 2 diabetes is a condition in which body does not make enough insulin, and the insulin that body produces does not work as well as it should. Body can also make too much sugar. When this happens, sugar [glucose] builds up in the blood. This can lead to serious medical problems.

RECENT APPROACH FOR TYPE 2 DIABETES – SITAGLIPTIN (JANUVIA)
*Sitagliptin (Januvia) helps to improve the level of insulin after a meal
*It decreases the amount of sugar made by the body
*It works when blood sugar is high, especially after a meal. This is when the body needs the greatest amount of help in lowering blood sugar. It also lowers blood sugar between meals. *It is unlikely to cause low sugar [Hypoglycemia] because it does not work when blood sugar is low
*It can be used alone or in combination with certain other medicine that lowers blood
sugar along with recommended diet and exercise program

CANNOT BE USED FOR PEOPLE WITH THE FOLLOWING CONDITIONS
*Type I Diabetes [who needs only insulin]
*Diabetic Ketoacidosis [increased ketones in blood and urine]
*Any kidney problems or any post or present medical problems *Allergy to Sitagliptin
* Children below 18 years of age
* Pregnancy and breast feeding woman

DOSAGES
*100 mg tablet is available in the market
*Once a day by mouth with or without food
*Diet and exercise can help our body use its blood sugar better. We should follow the
recommended diet, exercise and weight loss program while taking Sitagliptin

SIDE EFFECTS
Like other medicines, may cause side effects. But it was usually mild and did not cause patient to stop taking Sitagliptin. The side effects reported in patient treated with Sitagliptin were similar to side effects in patient treated with a tablet containing no medication [a placebo].
When used with sulfonylurea like Daonil, low blood sugar [Hypoglycemia] due to sulfonylurea can occur. Lower doses of sulfonylurea medicine may be required.
When Januvia [Sitagliptin] and Metformin [like Glyciphage] were started together the following side effects were reported.
*Diarrhea
*Indigestion
*Flatulence
*Vomiting
*Headache

OTHER EFFECTS OF THE MEDICINE
*Allergic reaction
*Upper respiratory infection
*Stuffy nose and sore throat

Disclaimer: All opinions and Information published here is for medical education only. It is not intended as and does not substitute for medical advice. If you are a patient, please see your doctor for evaluation of your individual case. Under no circumstances will the authors be liable to you for any direct or indirect damages arising in connection with use of this website