Under skin sensor to improve diabetes control

Staffs at Southampton General Hospital are using sensors placed under the skin of diabetic patients to measure the impact of exercise on glucose levels.

The devices are fitted to patients’ stomachs, who also wear watch-like armbands that check how active they are being.

The 12-month study will be the first in the UK to examine how activity impacts on blood glucose levels whilst also taking diet and insulin intake into account.

Thirty people aged 18 to 75 will take part in the trial; the aim of which is to provide further details on how to manage type one diabetes.

The sensors contain a tiny electrode, inserted under the skin that takes around 300 readings a day. This connects to a transmitter, which is attached to the skin with an adhesive patch.

Each participant can wear the devices for two weeks at a time with the sensors replaced every three days. Both electrode and transmitter are waterproof, light and durable. The armbands are worn for two periods of two weeks.

Study lead Professor Christopher Byrne, head of endocrinology and metabolism said: "At the moment, it is uncertain how day-to-day variation in physical activity influences blood glucose in people with Type 1 diabetes."

"But thanks to monitoring devices, such as the two we are trialling, we will gauge a better understanding of the link between physical activity and glucose control in diabetes."

It’s also hoped the study will help diabetics to understand the influence of exercise on glucose control and how it can help to reduce diabetic complications, he added.

Diabetes UK is funding the study.

Diabetes and Stem cell

Study: Stem Cells May Reverse Type 1 Diabetes – TIME

A stem cell treatment allows the regrowth of insulin-producing Beta cells in type 1 diabetes patients

Study: Stem Cells May Reverse Type 1 Diabetes

By Alice Park Monday, Apr. 13, 2009, Biophoto Associates / Photo Researchers

Researchers have used injections of patients’ own stem cells to reverse the course of type 1 diabetes, reports a research team from the University of São Paulo in Brazil and Northwestern University in Chicago.

The findings, published in the current issue of the Journal of the American Medical Association, exemplify the remarkable gains made by diabetes researchers, who are battling a continuously spreading disease that now affects nearly 8% of adults and children. (See the top 10 medical breakthroughs of 2008.)

The research team, led by Dr. Julio Voltarelli of the University of Sao Paulo, is the first to successfully treat type 1 diabetes patients with their own stem cells. The group first reported its initial achievement in 2007, with 15 type 1 diabetes patients who received their own stem cells and no longer needed insulin to control their blood sugar levels.

In the new study, a follow-up of their previous work, Voltarelli and his colleagues detailed the same success with an additional eight patients, and also confirmed that in the majority of them, the stem cell transplant led to an appreciable repopulation of functioning insulin-producing beta cells in the pancreas.

via Study: Stem Cells May Reverse Type 1 Diabetes – TIME.